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The Expression of Leptin and Its Receptor During Tumorigenesis of Diffuse Gliomas such as Astrocytoma and Oligodendroglioma- Grade II, III and IV (NOS)
BACKGROUND: Leptin, an adipocytokine functions via the leptin receptor, OB-Rb that contains an intact intracellular domain and activates the JAK/STAT signalling cascade. It stimulates growth, migration and invasion of cancer cells in vitro potentiating angiogenesis. Recently, the involvement of lept...
Autores principales: | Vokuda, Ramya S, Srinivas, B H, Madhugiri, Venkastesh S, Velusamy, Saravana Kumar, Verma, Surendra Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
West Asia Organization for Cancer Prevention
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897042/ https://www.ncbi.nlm.nih.gov/pubmed/30803210 http://dx.doi.org/10.31557/APJCP.2019.20.2.479 |
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