Cargando…
miR-509-5p Downregulation Is Associated With Male Infertility And Acts As A Suppressor In Testicular Germ Cell Tumor Cells Through Targeting MDM2
BACKGROUND: The dysregulation of microRNAs (miRNAs) has been linked with male infertility. miR-509-5p is highly expressed in testis and exerts suppressive effects on multiple types of human cancers. OBJECTIVES: Yet, whether miR-509-5p is connected with male infertility and plays a role in testicular...
Autores principales: | Sun, Jinxia, Niu, Lei, Gao, Shanxia, Yi, Xijuan, Chen, Jianxia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897070/ https://www.ncbi.nlm.nih.gov/pubmed/31819532 http://dx.doi.org/10.2147/OTT.S215998 |
Ejemplares similares
-
MicroRNA-509 acts as a tumor suppressor in tongue squamous cell carcinoma by targeting epidermal growth factor receptor
por: Hou, Chao, et al.
Publicado: (2017) -
Downregulation of KIF2C and TEKT2 is associated with male infertility and testicular carcinoma
por: Cao, Haiming, et al.
Publicado: (2021) -
Mir-509-5p joins the Mdm2/p53 feedback loop and regulates cancer cell growth
por: Ren, Z-J, et al.
Publicado: (2014) -
Testicular germ cell tumors
por: Albers, Peter
Publicado: (2021) -
Regressed testicular germ cell tumour in a post-pubertal male
por: Pickett, Lianne, et al.
Publicado: (2022)