Cargando…
Recalcitrant Issues and New Frontiers in Nano-Pharmacology
Packaging of old pharma drugs into new packaging “nanoparticles” is called nano-pharmacology and the products are called nano-based drugs. The inception of nano-pharmacology research and development (R&D) is marked by the approval of the first nano-based drug Doxil(®) in 1995 by the Food and Dru...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897283/ https://www.ncbi.nlm.nih.gov/pubmed/31849645 http://dx.doi.org/10.3389/fphar.2019.01369 |
_version_ | 1783476949570551808 |
---|---|
author | Bhardwaj, Vinay Kaushik, Ajeet Khatib, Ziad M. Nair, Madhavan McGoron, Anthony J. |
author_facet | Bhardwaj, Vinay Kaushik, Ajeet Khatib, Ziad M. Nair, Madhavan McGoron, Anthony J. |
author_sort | Bhardwaj, Vinay |
collection | PubMed |
description | Packaging of old pharma drugs into new packaging “nanoparticles” is called nano-pharmacology and the products are called nano-based drugs. The inception of nano-pharmacology research and development (R&D) is marked by the approval of the first nano-based drug Doxil(®) in 1995 by the Food and Drug Administration. However, even after more than two decades, today, there are only ∼20 nano-based drugs in the market to treat cancers and brain diseases. In this article we share the perspectives of nanotechnology scientists, engineers, and clinicians on the roadblocks in nano-pharmacology R&D. Also, we share our opinion on new frontiers in the field of nano-pharmacology R&D that may allow rapid and efficient transfer of nano-pharma technologies from R&D to market. |
format | Online Article Text |
id | pubmed-6897283 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-68972832019-12-17 Recalcitrant Issues and New Frontiers in Nano-Pharmacology Bhardwaj, Vinay Kaushik, Ajeet Khatib, Ziad M. Nair, Madhavan McGoron, Anthony J. Front Pharmacol Pharmacology Packaging of old pharma drugs into new packaging “nanoparticles” is called nano-pharmacology and the products are called nano-based drugs. The inception of nano-pharmacology research and development (R&D) is marked by the approval of the first nano-based drug Doxil(®) in 1995 by the Food and Drug Administration. However, even after more than two decades, today, there are only ∼20 nano-based drugs in the market to treat cancers and brain diseases. In this article we share the perspectives of nanotechnology scientists, engineers, and clinicians on the roadblocks in nano-pharmacology R&D. Also, we share our opinion on new frontiers in the field of nano-pharmacology R&D that may allow rapid and efficient transfer of nano-pharma technologies from R&D to market. Frontiers Media S.A. 2019-11-29 /pmc/articles/PMC6897283/ /pubmed/31849645 http://dx.doi.org/10.3389/fphar.2019.01369 Text en Copyright © 2019 Bhardwaj, Kaushik, Khatib, Nair and McGoron http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pharmacology Bhardwaj, Vinay Kaushik, Ajeet Khatib, Ziad M. Nair, Madhavan McGoron, Anthony J. Recalcitrant Issues and New Frontiers in Nano-Pharmacology |
title | Recalcitrant Issues and New Frontiers in Nano-Pharmacology |
title_full | Recalcitrant Issues and New Frontiers in Nano-Pharmacology |
title_fullStr | Recalcitrant Issues and New Frontiers in Nano-Pharmacology |
title_full_unstemmed | Recalcitrant Issues and New Frontiers in Nano-Pharmacology |
title_short | Recalcitrant Issues and New Frontiers in Nano-Pharmacology |
title_sort | recalcitrant issues and new frontiers in nano-pharmacology |
topic | Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897283/ https://www.ncbi.nlm.nih.gov/pubmed/31849645 http://dx.doi.org/10.3389/fphar.2019.01369 |
work_keys_str_mv | AT bhardwajvinay recalcitrantissuesandnewfrontiersinnanopharmacology AT kaushikajeet recalcitrantissuesandnewfrontiersinnanopharmacology AT khatibziadm recalcitrantissuesandnewfrontiersinnanopharmacology AT nairmadhavan recalcitrantissuesandnewfrontiersinnanopharmacology AT mcgoronanthonyj recalcitrantissuesandnewfrontiersinnanopharmacology |