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Synthesis, Antimicrobial Activity, Structure-Activity Relationship, and Molecular Docking Studies of Indole Diketopiperazine Alkaloids

Strategies for the synthesis of indole diketopiperazine alkaloids (indole DKPs) have been described and involve three analogs of indole DKPs. The antimicrobial activity and structure-activity relationship (SAR) of 24 indole DKPs were explored. Compounds 3b and 3c were found to be the most active, wi...

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Detalles Bibliográficos
Autores principales: Jia, Bin, Ma, Yang-min, Liu, Bin, Chen, Pu, Hu, Yan, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897290/
https://www.ncbi.nlm.nih.gov/pubmed/31850323
http://dx.doi.org/10.3389/fchem.2019.00837