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Thyroid and Heart: Severe Three Vessel Coronary Artery Disease in a Middle-Aged Female with Hypothyroidism

Hypothyroidism is a common medical condition. The low metabolic state in hypothyroidism leads to significant cardiovascular and hemodynamic changes. Hypothyroidism is associated with heart failure, diastolic hypertension, atherosclerosis, coronary artery disease (CAD), and decreased insulin sensitiv...

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Detalles Bibliográficos
Autores principales: Muneer, Ramsha, Naqvi, Syed Arsalan Ahmed, Gul, Owais, Zaidi, Syed Danish H, Dar, Mudassir Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897348/
https://www.ncbi.nlm.nih.gov/pubmed/31857927
http://dx.doi.org/10.7759/cureus.6095
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author Muneer, Ramsha
Naqvi, Syed Arsalan Ahmed
Gul, Owais
Zaidi, Syed Danish H
Dar, Mudassir Iqbal
author_facet Muneer, Ramsha
Naqvi, Syed Arsalan Ahmed
Gul, Owais
Zaidi, Syed Danish H
Dar, Mudassir Iqbal
author_sort Muneer, Ramsha
collection PubMed
description Hypothyroidism is a common medical condition. The low metabolic state in hypothyroidism leads to significant cardiovascular and hemodynamic changes. Hypothyroidism is associated with heart failure, diastolic hypertension, atherosclerosis, coronary artery disease (CAD), and decreased insulin sensitivity. Similarly, the administration of levothyroxine worsens the cardiovascular disease by establishing a supply-demand mismatch. Here, we present a case of a 45-year-old woman with hypothyroidism who presented to us with exertional chest pain and later got diagnosed with severe three-vessel disease. Coronary artery bypass grafting (CABG) surgery was planned after the establishment of euthyroid state.
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spelling pubmed-68973482019-12-19 Thyroid and Heart: Severe Three Vessel Coronary Artery Disease in a Middle-Aged Female with Hypothyroidism Muneer, Ramsha Naqvi, Syed Arsalan Ahmed Gul, Owais Zaidi, Syed Danish H Dar, Mudassir Iqbal Cureus Endocrinology/Diabetes/Metabolism Hypothyroidism is a common medical condition. The low metabolic state in hypothyroidism leads to significant cardiovascular and hemodynamic changes. Hypothyroidism is associated with heart failure, diastolic hypertension, atherosclerosis, coronary artery disease (CAD), and decreased insulin sensitivity. Similarly, the administration of levothyroxine worsens the cardiovascular disease by establishing a supply-demand mismatch. Here, we present a case of a 45-year-old woman with hypothyroidism who presented to us with exertional chest pain and later got diagnosed with severe three-vessel disease. Coronary artery bypass grafting (CABG) surgery was planned after the establishment of euthyroid state. Cureus 2019-11-08 /pmc/articles/PMC6897348/ /pubmed/31857927 http://dx.doi.org/10.7759/cureus.6095 Text en Copyright © 2019, Muneer et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Muneer, Ramsha
Naqvi, Syed Arsalan Ahmed
Gul, Owais
Zaidi, Syed Danish H
Dar, Mudassir Iqbal
Thyroid and Heart: Severe Three Vessel Coronary Artery Disease in a Middle-Aged Female with Hypothyroidism
title Thyroid and Heart: Severe Three Vessel Coronary Artery Disease in a Middle-Aged Female with Hypothyroidism
title_full Thyroid and Heart: Severe Three Vessel Coronary Artery Disease in a Middle-Aged Female with Hypothyroidism
title_fullStr Thyroid and Heart: Severe Three Vessel Coronary Artery Disease in a Middle-Aged Female with Hypothyroidism
title_full_unstemmed Thyroid and Heart: Severe Three Vessel Coronary Artery Disease in a Middle-Aged Female with Hypothyroidism
title_short Thyroid and Heart: Severe Three Vessel Coronary Artery Disease in a Middle-Aged Female with Hypothyroidism
title_sort thyroid and heart: severe three vessel coronary artery disease in a middle-aged female with hypothyroidism
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897348/
https://www.ncbi.nlm.nih.gov/pubmed/31857927
http://dx.doi.org/10.7759/cureus.6095
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