C5aR agonist enhances phagocytosis of fibrillar and non-fibrillar Aβ amyloid and preserves memory in a mouse model of familial Alzheimer’s disease

According to the amyloid hypothesis of Alzheimer’s disease (AD) the deposition of prefibrillar and fibrillar Aβ peptide sets off the pathogenic cascades of neuroinflammation and neurodegeneration that lead to synaptic and neuronal loss resulting in cognitive decline. Various approaches to reduce amy...

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Detalles Bibliográficos
Autores principales: Panayiotou, Elena, Fella, Eleni, Andreou, Savanna, Papacharalambous, Revekka, Gerasimou, Petroula, Costeas, Paul, Angeli, Stella, Kousiappa, Ioanna, Papacostas, Savvas, Kyriakides, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897413/
https://www.ncbi.nlm.nih.gov/pubmed/31809505
http://dx.doi.org/10.1371/journal.pone.0225417

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