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Unravelling Receptor and RGD Motif Dependence of Retargeted Adenoviral Vectors using Advanced Tumor Model Systems

Recent advances in engineering adenoviruses are paving the way for new therapeutic gene delivery approaches in cancer. However, there is limited knowledge regarding the impact of adenoviral retargeting on transduction efficiency in more complex tumor architectures, and the role of the RGD loop at th...

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Detalles Bibliográficos
Autores principales:	Chernyavska, M., Schmid, M., Freitag, P. C., Palacio-Castañeda, V., Piruska, A., Huck, W. T. S., Plückthun, A., Verdurmen, W. P. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897923/ https://www.ncbi.nlm.nih.gov/pubmed/31811202 http://dx.doi.org/10.1038/s41598-019-54939-9

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