Secretome analysis of patient-derived GBM tumor spheres identifies midkine as a potent therapeutic target

Glioblastoma (GBM) is the most lethal primary brain tumor with few treatment options. The survival of glioma-initiating cells (GICs) is one of the major factors contributing to treatment failure. GICs frequently produce and respond to their own growth factors that support cell proliferation and surv...

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Detalles Bibliográficos
Autores principales: Han, Suji, Shin, Hyemi, Lee, Jin-Ku, Liu, Zhaoqi, Rabadan, Raul, Lee, Jeongwu, Shin, Jihye, Lee, Cheolju, Yang, Heekyoung, Kim, Donggeon, Kim, Sung Heon, Kim, Jooyeon, Oh, Jeong-Woo, Kong, Doo-Sik, Lee, Jung-Il, Seol, Ho Jun, Choi, Jung Won, Kang, Hyun Ju, Nam, Do-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897967/
https://www.ncbi.nlm.nih.gov/pubmed/31811117
http://dx.doi.org/10.1038/s12276-019-0351-y

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