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Comparison of Anterior only and Combined Anterior and Posterior Approach in Treating Lumbosacral Tuberculosis

A combined anterior and posterior (AP) surgical approach is a popular treatment modality of lumbosacral tuberculosis, but it is often traumatic and complicated. The present study aims to find whether the anterior only approach with the ARCH plate system is less invasive than the AP approach in treat...

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Autores principales: Sun, Dong, Zhang, Ze-hua, Mei, Gang, Hou, Tian-yong, Li, Yang, Xu, Jian-Zhong, Luo, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898139/
https://www.ncbi.nlm.nih.gov/pubmed/31811159
http://dx.doi.org/10.1038/s41598-019-53800-3
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author Sun, Dong
Zhang, Ze-hua
Mei, Gang
Hou, Tian-yong
Li, Yang
Xu, Jian-Zhong
Luo, Fei
author_facet Sun, Dong
Zhang, Ze-hua
Mei, Gang
Hou, Tian-yong
Li, Yang
Xu, Jian-Zhong
Luo, Fei
author_sort Sun, Dong
collection PubMed
description A combined anterior and posterior (AP) surgical approach is a popular treatment modality of lumbosacral tuberculosis, but it is often traumatic and complicated. The present study aims to find whether the anterior only approach with the ARCH plate system is less invasive than the AP approach in treating lumbosacral tuberculosis. The ARCH plate system is an innovative anatomic lumbosacral anterior multi-directional locking plate system which was devised with due consideration to the anatomic features of the lumbosacral spine and irregular destruction of involved vertebral endplates. In this retrospective study, 32 patients with lumbosacral tuberculosis underwent surgeries via either the anterior only approach (ARCH group, 18 patients) using the ARCH system or the conventional combined anterior and posterior approach (AP group, 14 patients). American Spinal Injury Association (ASIA) scores, Visual Analogue Scale (VAS) scores, Oswestry Disability Index (ODI), bone union status, ESR, CRP, intervertebral foraminal height between L5 and S1, the vertical height between the anterior upper edge of L5 and S1 vertebral body, lumbosacral angle, and the physiological lordosis of between L1 and S1 from both groups were recorded and compared. All patients were followed up for at least two years. The average duration of operation, blood loss, and length of hospital admission of the ARCH group (154.6 min, 361.1 ml&18.3days) was significantly smaller and shorter(p < 0.001, p < 0.001 & p = 0.008) that those of the AP group(465.5 min, 814.3 ml & 24.6days). The ODI score(p = 0.08, 0.471, 0.06, 0.07, 0.107), the VAS score(p = 0.099, 0.249, 0.073, 0.103, 0.273), the intervertebral foraminal height between L5 and S1(p = 0.826, 0.073, 0.085), L5-S1 height(p = 0.057, 0.234, 0.094), lumbosacral angle(p = 0.052, 0.242, 0.825), and L5-S1 lordosis(p = 0.146, 0.129, 0.053) of both groups showed no significant difference in any of the time points. The anterior only approach using the ARCH system is as effective as the combined anterior and posterior approach and is less traumatic in treating lumbosacral tuberculosis.
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spelling pubmed-68981392019-12-12 Comparison of Anterior only and Combined Anterior and Posterior Approach in Treating Lumbosacral Tuberculosis Sun, Dong Zhang, Ze-hua Mei, Gang Hou, Tian-yong Li, Yang Xu, Jian-Zhong Luo, Fei Sci Rep Article A combined anterior and posterior (AP) surgical approach is a popular treatment modality of lumbosacral tuberculosis, but it is often traumatic and complicated. The present study aims to find whether the anterior only approach with the ARCH plate system is less invasive than the AP approach in treating lumbosacral tuberculosis. The ARCH plate system is an innovative anatomic lumbosacral anterior multi-directional locking plate system which was devised with due consideration to the anatomic features of the lumbosacral spine and irregular destruction of involved vertebral endplates. In this retrospective study, 32 patients with lumbosacral tuberculosis underwent surgeries via either the anterior only approach (ARCH group, 18 patients) using the ARCH system or the conventional combined anterior and posterior approach (AP group, 14 patients). American Spinal Injury Association (ASIA) scores, Visual Analogue Scale (VAS) scores, Oswestry Disability Index (ODI), bone union status, ESR, CRP, intervertebral foraminal height between L5 and S1, the vertical height between the anterior upper edge of L5 and S1 vertebral body, lumbosacral angle, and the physiological lordosis of between L1 and S1 from both groups were recorded and compared. All patients were followed up for at least two years. The average duration of operation, blood loss, and length of hospital admission of the ARCH group (154.6 min, 361.1 ml&18.3days) was significantly smaller and shorter(p < 0.001, p < 0.001 & p = 0.008) that those of the AP group(465.5 min, 814.3 ml & 24.6days). The ODI score(p = 0.08, 0.471, 0.06, 0.07, 0.107), the VAS score(p = 0.099, 0.249, 0.073, 0.103, 0.273), the intervertebral foraminal height between L5 and S1(p = 0.826, 0.073, 0.085), L5-S1 height(p = 0.057, 0.234, 0.094), lumbosacral angle(p = 0.052, 0.242, 0.825), and L5-S1 lordosis(p = 0.146, 0.129, 0.053) of both groups showed no significant difference in any of the time points. The anterior only approach using the ARCH system is as effective as the combined anterior and posterior approach and is less traumatic in treating lumbosacral tuberculosis. Nature Publishing Group UK 2019-12-06 /pmc/articles/PMC6898139/ /pubmed/31811159 http://dx.doi.org/10.1038/s41598-019-53800-3 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Sun, Dong
Zhang, Ze-hua
Mei, Gang
Hou, Tian-yong
Li, Yang
Xu, Jian-Zhong
Luo, Fei
Comparison of Anterior only and Combined Anterior and Posterior Approach in Treating Lumbosacral Tuberculosis
title Comparison of Anterior only and Combined Anterior and Posterior Approach in Treating Lumbosacral Tuberculosis
title_full Comparison of Anterior only and Combined Anterior and Posterior Approach in Treating Lumbosacral Tuberculosis
title_fullStr Comparison of Anterior only and Combined Anterior and Posterior Approach in Treating Lumbosacral Tuberculosis
title_full_unstemmed Comparison of Anterior only and Combined Anterior and Posterior Approach in Treating Lumbosacral Tuberculosis
title_short Comparison of Anterior only and Combined Anterior and Posterior Approach in Treating Lumbosacral Tuberculosis
title_sort comparison of anterior only and combined anterior and posterior approach in treating lumbosacral tuberculosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898139/
https://www.ncbi.nlm.nih.gov/pubmed/31811159
http://dx.doi.org/10.1038/s41598-019-53800-3
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