XIAP Interaction with E2F1 and Sp1 via its BIR2 and BIR3 domains specific activated MMP2 to promote bladder cancer invasion

XIAP has generally been thought to function in bladder cancer. However, the potential function of structure-based function of XIAP in human BC invasion has not been well explored before. We show here that ectopic expression of the BIR domains of XIAP specifically resulted in MMP2 activation and cell...

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Detalles Bibliográficos
Autores principales: Xu, Jiheng, Hua, Xiaohui, Yang, Rui, Jin, Honglei, Li, Jingxia, Zhu, Junlan, Tian, Zhongxian, Huang, Maowen, Jiang, Guosong, Huang, Haishan, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898186/
https://www.ncbi.nlm.nih.gov/pubmed/31811115
http://dx.doi.org/10.1038/s41389-019-0181-8

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