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Mapping lung cancer epithelial-mesenchymal transition states and trajectories with single-cell resolution

Elucidating the spectrum of epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) states in clinical samples promises insights on cancer progression and drug resistance. Using mass cytometry time-course analysis, we resolve lung cancer EMT states through TGFβ-treatment...

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Detalles Bibliográficos
Autores principales:	Karacosta, Loukia G., Anchang, Benedict, Ignatiadis, Nikolaos, Kimmey, Samuel C., Benson, Jalen A., Shrager, Joseph B., Tibshirani, Robert, Bendall, Sean C., Plevritis, Sylvia K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898514/ https://www.ncbi.nlm.nih.gov/pubmed/31811131 http://dx.doi.org/10.1038/s41467-019-13441-6

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