Transcription activity contributes to the firing of non-constitutive origins in African trypanosomes helping to maintain robustness in S-phase duration

The co-synthesis of DNA and RNA potentially generates conflicts between replication and transcription, which can lead to genomic instability. In trypanosomatids, eukaryotic parasites that perform polycistronic transcription, this phenomenon and its consequences are still little studied. Here, we sho...

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Detalles Bibliográficos
Autores principales: da Silva, Marcelo S., Cayres-Silva, Gustavo R., Vitarelli, Marcela O., Marin, Paula A., Hiraiwa, Priscila M., Araújo, Christiane B., Scholl, Bruno B., Ávila, Andrea R., McCulloch, Richard, Reis, Marcelo S., Elias, Maria Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898680/
https://www.ncbi.nlm.nih.gov/pubmed/31811174
http://dx.doi.org/10.1038/s41598-019-54366-w

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