Features of non-activation dendritic state and immune deficiency in blastic plasmacytoid dendritic cell neoplasm (BPDCN)

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, male-predominant hematologic malignancy with poor outcomes and with just one recently approved agent (tagraxofusp). It is characterized by the abnormal proliferation of precursor plasmacytoid dendritic cells (pDCs) with morphologic and...

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Detalles Bibliográficos
Autores principales: Beird, Hannah C., Khan, Maliha, Wang, Feng, Alfayez, Mansour, Cai, Tianyu, Zhao, Li, Khoury, Joseph, Futreal, P. Andrew, Konopleva, Marina, Pemmaraju, Naveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898719/
https://www.ncbi.nlm.nih.gov/pubmed/31811114
http://dx.doi.org/10.1038/s41408-019-0262-0

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