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Knowledge of HIV Status Is Associated With a Decrease in the Severity of Depressive Symptoms Among Female Sex Workers in Uganda and Zambia

Knowledge of HIV-positive status may result in depressive symptoms, which may be a concern to scaling novel HIV testing interventions that move testing outside the health system and away from counselor support. SETTING: Uganda and Zambia. METHODS: We used longitudinal data from 2 female sex worker (...

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Autores principales: Ortblad, Katrina F., Musoke, Daniel Kibuuka, Chanda, Michael M., Ngabirano, Thomson, Velloza, Jennifer, Haberer, Jessica E., McConnell, Margaret, Oldenburg, Catherine E., Bärnighausen, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898780/
https://www.ncbi.nlm.nih.gov/pubmed/31633611
http://dx.doi.org/10.1097/QAI.0000000000002224
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author Ortblad, Katrina F.
Musoke, Daniel Kibuuka
Chanda, Michael M.
Ngabirano, Thomson
Velloza, Jennifer
Haberer, Jessica E.
McConnell, Margaret
Oldenburg, Catherine E.
Bärnighausen, Till
author_facet Ortblad, Katrina F.
Musoke, Daniel Kibuuka
Chanda, Michael M.
Ngabirano, Thomson
Velloza, Jennifer
Haberer, Jessica E.
McConnell, Margaret
Oldenburg, Catherine E.
Bärnighausen, Till
author_sort Ortblad, Katrina F.
collection PubMed
description Knowledge of HIV-positive status may result in depressive symptoms, which may be a concern to scaling novel HIV testing interventions that move testing outside the health system and away from counselor support. SETTING: Uganda and Zambia. METHODS: We used longitudinal data from 2 female sex worker (FSW) cohorts in Uganda (n = 960) and Zambia (n = 965). Over 4 months, participants had ample opportunity to HIV testing using standard-of-care services or self-tests. At baseline and 4 months, we measured participants' perceived knowledge of HIV status, severity of depressive symptoms (continuous PHQ-9 scale, 0–27 points), and prevalence of likely depression (PHQ-9 scores ≥10). We estimated associations using individual fixed-effects estimation. RESULTS: Compared with unknown HIV status, knowledge of HIV-negative status was significantly associated with a decrease in depressive symptoms of 1.06 points in Uganda (95% CI −1.79 to −0.34) and 1.68 points in Zambia (95% CI −2.70 to −0.62). Knowledge of HIV-positive status was significantly associated with a decrease in depressive symptoms of 1.01 points in Uganda (95% CI −1.82 to −0.20) and 1.98 points in Zambia (95% CI −3.09 to −0.88). The prevalence of likely depression was not associated with knowledge of HIV status in Uganda but was associated with a 14.1% decrease with knowledge of HIV-negative status (95% CI −22.1% to −6.0%) and a 14.3% decrease with knowledge of HIV-positive status (95% CI −23.9% to −4.5%) in Zambia. CONCLUSIONS: Knowledge of HIV status, be it positive or negative, was significantly associated with a decrease in depressive symptoms in 2 FSW populations. The expansion of HIV testing programs may have mental health benefits for FSWs.
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spelling pubmed-68987802020-02-03 Knowledge of HIV Status Is Associated With a Decrease in the Severity of Depressive Symptoms Among Female Sex Workers in Uganda and Zambia Ortblad, Katrina F. Musoke, Daniel Kibuuka Chanda, Michael M. Ngabirano, Thomson Velloza, Jennifer Haberer, Jessica E. McConnell, Margaret Oldenburg, Catherine E. Bärnighausen, Till J Acquir Immune Defic Syndr Prevention Research Knowledge of HIV-positive status may result in depressive symptoms, which may be a concern to scaling novel HIV testing interventions that move testing outside the health system and away from counselor support. SETTING: Uganda and Zambia. METHODS: We used longitudinal data from 2 female sex worker (FSW) cohorts in Uganda (n = 960) and Zambia (n = 965). Over 4 months, participants had ample opportunity to HIV testing using standard-of-care services or self-tests. At baseline and 4 months, we measured participants' perceived knowledge of HIV status, severity of depressive symptoms (continuous PHQ-9 scale, 0–27 points), and prevalence of likely depression (PHQ-9 scores ≥10). We estimated associations using individual fixed-effects estimation. RESULTS: Compared with unknown HIV status, knowledge of HIV-negative status was significantly associated with a decrease in depressive symptoms of 1.06 points in Uganda (95% CI −1.79 to −0.34) and 1.68 points in Zambia (95% CI −2.70 to −0.62). Knowledge of HIV-positive status was significantly associated with a decrease in depressive symptoms of 1.01 points in Uganda (95% CI −1.82 to −0.20) and 1.98 points in Zambia (95% CI −3.09 to −0.88). The prevalence of likely depression was not associated with knowledge of HIV status in Uganda but was associated with a 14.1% decrease with knowledge of HIV-negative status (95% CI −22.1% to −6.0%) and a 14.3% decrease with knowledge of HIV-positive status (95% CI −23.9% to −4.5%) in Zambia. CONCLUSIONS: Knowledge of HIV status, be it positive or negative, was significantly associated with a decrease in depressive symptoms in 2 FSW populations. The expansion of HIV testing programs may have mental health benefits for FSWs. JAIDS Journal of Acquired Immune Deficiency Syndromes 2020-01-01 2019-10-16 /pmc/articles/PMC6898780/ /pubmed/31633611 http://dx.doi.org/10.1097/QAI.0000000000002224 Text en Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Prevention Research
Ortblad, Katrina F.
Musoke, Daniel Kibuuka
Chanda, Michael M.
Ngabirano, Thomson
Velloza, Jennifer
Haberer, Jessica E.
McConnell, Margaret
Oldenburg, Catherine E.
Bärnighausen, Till
Knowledge of HIV Status Is Associated With a Decrease in the Severity of Depressive Symptoms Among Female Sex Workers in Uganda and Zambia
title Knowledge of HIV Status Is Associated With a Decrease in the Severity of Depressive Symptoms Among Female Sex Workers in Uganda and Zambia
title_full Knowledge of HIV Status Is Associated With a Decrease in the Severity of Depressive Symptoms Among Female Sex Workers in Uganda and Zambia
title_fullStr Knowledge of HIV Status Is Associated With a Decrease in the Severity of Depressive Symptoms Among Female Sex Workers in Uganda and Zambia
title_full_unstemmed Knowledge of HIV Status Is Associated With a Decrease in the Severity of Depressive Symptoms Among Female Sex Workers in Uganda and Zambia
title_short Knowledge of HIV Status Is Associated With a Decrease in the Severity of Depressive Symptoms Among Female Sex Workers in Uganda and Zambia
title_sort knowledge of hiv status is associated with a decrease in the severity of depressive symptoms among female sex workers in uganda and zambia
topic Prevention Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898780/
https://www.ncbi.nlm.nih.gov/pubmed/31633611
http://dx.doi.org/10.1097/QAI.0000000000002224
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