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Prospective virome analyses in young children at increased genetic risk for type 1 diabetes
Viruses are implicated in the autoimmune destruction of the pancreatic islet β-cells that results in insulin deficiency and type 1 diabetes (T1D)(1–4). Certain enteroviruses can infect β-cells in vitro(5), have been detected in pancreatic islets of T1D patients(6) and shown an association with T1D i...
Autores principales: | Vehik, Kendra, Lynch, Kristian F., Wong, Matthew C., Tian, Xiangjun, Ross, Matthew C., Gibbs, Richard A., Ajami, Nadim J., Petrosino, Joseph F., Rewers, Marian, Toppari, Jorma, Ziegler, Anette G., She, Jin-Xiong, Lernmark, Ake, Akolkar, Beena, Hagopian, William A., Schatz, Desmond A., Krischer, Jeffrey P., Hyöty, Heikki, Richard E., Lloyd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898786/ https://www.ncbi.nlm.nih.gov/pubmed/31792456 http://dx.doi.org/10.1038/s41591-019-0667-0 |
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