Paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report

INTRODUCTION: Pyoderma gangrenosum is a rare, idiopathic, inflammatory, neutrophilic dermatitis characterized by sterile skin ulceration. It can be associated with an underlying pathology, especially inflammatory bowel disease and hematological malignancies. Its association with a malignant patholog...

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Autores principales: Alassani, Fousséni, Kassang, Panawe, Amouzou, Efoe-Ga, Tchangai, Boyodi, Sakiye, Kossi Abossisso, Darré, Tchin, Saka, Bayaki, Attipou, Komla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898921/
https://www.ncbi.nlm.nih.gov/pubmed/31810486
http://dx.doi.org/10.1186/s13256-019-2290-6
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author Alassani, Fousséni
Kassang, Panawe
Amouzou, Efoe-Ga
Tchangai, Boyodi
Sakiye, Kossi Abossisso
Darré, Tchin
Saka, Bayaki
Attipou, Komla
author_facet Alassani, Fousséni
Kassang, Panawe
Amouzou, Efoe-Ga
Tchangai, Boyodi
Sakiye, Kossi Abossisso
Darré, Tchin
Saka, Bayaki
Attipou, Komla
author_sort Alassani, Fousséni
collection PubMed
description INTRODUCTION: Pyoderma gangrenosum is a rare, idiopathic, inflammatory, neutrophilic dermatitis characterized by sterile skin ulceration. It can be associated with an underlying pathology, especially inflammatory bowel disease and hematological malignancies. Its association with a malignant pathology in the context of a paraneoplastic syndrome is more commonly described in hematological malignancies, with solid tumors being rare. CASE REPORT: We report a case of a 39-year-old West African man with pyoderma gangrenosum that developed 6 months before the clinical expression of rectosigmoid junction cancer. The removal of the cancer resulted in the patient’s recovery. CONCLUSION: Recurrent pyoderma gangrenosum lesions may be the expression of colonic adenocarcinoma in paraneoplastic syndrome and require colonoscopy, especially in at-risk patients.
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spelling pubmed-68989212019-12-11 Paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report Alassani, Fousséni Kassang, Panawe Amouzou, Efoe-Ga Tchangai, Boyodi Sakiye, Kossi Abossisso Darré, Tchin Saka, Bayaki Attipou, Komla J Med Case Rep Case Report INTRODUCTION: Pyoderma gangrenosum is a rare, idiopathic, inflammatory, neutrophilic dermatitis characterized by sterile skin ulceration. It can be associated with an underlying pathology, especially inflammatory bowel disease and hematological malignancies. Its association with a malignant pathology in the context of a paraneoplastic syndrome is more commonly described in hematological malignancies, with solid tumors being rare. CASE REPORT: We report a case of a 39-year-old West African man with pyoderma gangrenosum that developed 6 months before the clinical expression of rectosigmoid junction cancer. The removal of the cancer resulted in the patient’s recovery. CONCLUSION: Recurrent pyoderma gangrenosum lesions may be the expression of colonic adenocarcinoma in paraneoplastic syndrome and require colonoscopy, especially in at-risk patients. BioMed Central 2019-12-07 /pmc/articles/PMC6898921/ /pubmed/31810486 http://dx.doi.org/10.1186/s13256-019-2290-6 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Alassani, Fousséni
Kassang, Panawe
Amouzou, Efoe-Ga
Tchangai, Boyodi
Sakiye, Kossi Abossisso
Darré, Tchin
Saka, Bayaki
Attipou, Komla
Paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report
title Paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report
title_full Paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report
title_fullStr Paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report
title_full_unstemmed Paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report
title_short Paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report
title_sort paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898921/
https://www.ncbi.nlm.nih.gov/pubmed/31810486
http://dx.doi.org/10.1186/s13256-019-2290-6
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