A novel fluorescent biosensor based on dendritic DNA nanostructure in combination with ligase reaction for ultrasensitive detection of DNA methylation

BACKGROUND: DNA methylation detection is indispensable for the diagnosis and prognosis of various diseases including malignancies. Hence, it is crucial to develop a simple, sensitive, and specific detection strategy. METHODS: A novel fluorescent biosensor was developed based on a simple dual signal...

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Detalles Bibliográficos
Autores principales: Zhang, Shu, Huang, Jian, Lu, Jingrun, Liu, Min, Li, Yan, Fang, Lichao, Huang, Hui, Huang, Jianjun, Mo, Fei, Zheng, Junsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898925/
https://www.ncbi.nlm.nih.gov/pubmed/31812164
http://dx.doi.org/10.1186/s12951-019-0552-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898925/
https://www.ncbi.nlm.nih.gov/pubmed/31812164
http://dx.doi.org/10.1186/s12951-019-0552-5

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