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A novel fluorescent biosensor based on dendritic DNA nanostructure in combination with ligase reaction for ultrasensitive detection of DNA methylation
BACKGROUND: DNA methylation detection is indispensable for the diagnosis and prognosis of various diseases including malignancies. Hence, it is crucial to develop a simple, sensitive, and specific detection strategy. METHODS: A novel fluorescent biosensor was developed based on a simple dual signal...
Autores principales: | Zhang, Shu, Huang, Jian, Lu, Jingrun, Liu, Min, Li, Yan, Fang, Lichao, Huang, Hui, Huang, Jianjun, Mo, Fei, Zheng, Junsong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898925/ https://www.ncbi.nlm.nih.gov/pubmed/31812164 http://dx.doi.org/10.1186/s12951-019-0552-5 |
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