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Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study

BACKGROUND: Endovascular treatment (EVT) is now considered the gold standard for select patient populations with anterior circulation stroke; however, data on the treatment of posterior circulation stroke are less clear. This study aims to determine the characteristics and treatment outcomes of pati...

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Autores principales: Sun, Xuan, Tong, Xu, Gao, Feng, Lao, Huiting, Miao, Zhongrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898927/
https://www.ncbi.nlm.nih.gov/pubmed/31810447
http://dx.doi.org/10.1186/s12883-019-1551-8
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author Sun, Xuan
Tong, Xu
Gao, Feng
Lao, Huiting
Miao, Zhongrong
author_facet Sun, Xuan
Tong, Xu
Gao, Feng
Lao, Huiting
Miao, Zhongrong
author_sort Sun, Xuan
collection PubMed
description BACKGROUND: Endovascular treatment (EVT) is now considered the gold standard for select patient populations with anterior circulation stroke; however, data on the treatment of posterior circulation stroke are less clear. This study aims to determine the characteristics and treatment outcomes of patients with acute basilar artery occlusion (BAO) and to evaluate the effectiveness and safety of EVT for patients with acute BAO in a high-volume stroke center. METHODS: This study included 187 consecutive patients with acute BAO who underwent EVT from January 2012 to July 2018 in the Beijing Tiantan Hospital. The baseline characteristics, procedure parameters, and functional outcome were assessed. RESULTS: Among the 187 patients, 138 (73.8%) underwent mechanical thrombectomy with a stent retriever, 33 (17.6%) underwent direct intracranial angioplasty (balloon dilation and/or stent implantation) for underlying severe intracranial atherosclerotic disease, and 91 (48.7%) underwent combined mechanical thrombectomy and angioplasty. Successful recanalization [modified Thrombolysis in Cerebral Infarction (mTICI) grade 2b-3] was achieved in 158 patients (84.5%). Overall, the rates of functional independence [modified Rankin Scale (mRS) 0–2] and favorable outcome (mRS 0–3) at 90 days were 36.4 and 49.2%, respectively, and 90-day all-cause mortality was 20.3%. CONCLUSION: EVT was effective and safe for treating patients with acute BAO.
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spelling pubmed-68989272019-12-11 Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study Sun, Xuan Tong, Xu Gao, Feng Lao, Huiting Miao, Zhongrong BMC Neurol Research Article BACKGROUND: Endovascular treatment (EVT) is now considered the gold standard for select patient populations with anterior circulation stroke; however, data on the treatment of posterior circulation stroke are less clear. This study aims to determine the characteristics and treatment outcomes of patients with acute basilar artery occlusion (BAO) and to evaluate the effectiveness and safety of EVT for patients with acute BAO in a high-volume stroke center. METHODS: This study included 187 consecutive patients with acute BAO who underwent EVT from January 2012 to July 2018 in the Beijing Tiantan Hospital. The baseline characteristics, procedure parameters, and functional outcome were assessed. RESULTS: Among the 187 patients, 138 (73.8%) underwent mechanical thrombectomy with a stent retriever, 33 (17.6%) underwent direct intracranial angioplasty (balloon dilation and/or stent implantation) for underlying severe intracranial atherosclerotic disease, and 91 (48.7%) underwent combined mechanical thrombectomy and angioplasty. Successful recanalization [modified Thrombolysis in Cerebral Infarction (mTICI) grade 2b-3] was achieved in 158 patients (84.5%). Overall, the rates of functional independence [modified Rankin Scale (mRS) 0–2] and favorable outcome (mRS 0–3) at 90 days were 36.4 and 49.2%, respectively, and 90-day all-cause mortality was 20.3%. CONCLUSION: EVT was effective and safe for treating patients with acute BAO. BioMed Central 2019-12-06 /pmc/articles/PMC6898927/ /pubmed/31810447 http://dx.doi.org/10.1186/s12883-019-1551-8 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Sun, Xuan
Tong, Xu
Gao, Feng
Lao, Huiting
Miao, Zhongrong
Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study
title Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study
title_full Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study
title_fullStr Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study
title_full_unstemmed Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study
title_short Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study
title_sort endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898927/
https://www.ncbi.nlm.nih.gov/pubmed/31810447
http://dx.doi.org/10.1186/s12883-019-1551-8
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