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Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study
BACKGROUND: Endovascular treatment (EVT) is now considered the gold standard for select patient populations with anterior circulation stroke; however, data on the treatment of posterior circulation stroke are less clear. This study aims to determine the characteristics and treatment outcomes of pati...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898927/ https://www.ncbi.nlm.nih.gov/pubmed/31810447 http://dx.doi.org/10.1186/s12883-019-1551-8 |
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author | Sun, Xuan Tong, Xu Gao, Feng Lao, Huiting Miao, Zhongrong |
author_facet | Sun, Xuan Tong, Xu Gao, Feng Lao, Huiting Miao, Zhongrong |
author_sort | Sun, Xuan |
collection | PubMed |
description | BACKGROUND: Endovascular treatment (EVT) is now considered the gold standard for select patient populations with anterior circulation stroke; however, data on the treatment of posterior circulation stroke are less clear. This study aims to determine the characteristics and treatment outcomes of patients with acute basilar artery occlusion (BAO) and to evaluate the effectiveness and safety of EVT for patients with acute BAO in a high-volume stroke center. METHODS: This study included 187 consecutive patients with acute BAO who underwent EVT from January 2012 to July 2018 in the Beijing Tiantan Hospital. The baseline characteristics, procedure parameters, and functional outcome were assessed. RESULTS: Among the 187 patients, 138 (73.8%) underwent mechanical thrombectomy with a stent retriever, 33 (17.6%) underwent direct intracranial angioplasty (balloon dilation and/or stent implantation) for underlying severe intracranial atherosclerotic disease, and 91 (48.7%) underwent combined mechanical thrombectomy and angioplasty. Successful recanalization [modified Thrombolysis in Cerebral Infarction (mTICI) grade 2b-3] was achieved in 158 patients (84.5%). Overall, the rates of functional independence [modified Rankin Scale (mRS) 0–2] and favorable outcome (mRS 0–3) at 90 days were 36.4 and 49.2%, respectively, and 90-day all-cause mortality was 20.3%. CONCLUSION: EVT was effective and safe for treating patients with acute BAO. |
format | Online Article Text |
id | pubmed-6898927 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-68989272019-12-11 Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study Sun, Xuan Tong, Xu Gao, Feng Lao, Huiting Miao, Zhongrong BMC Neurol Research Article BACKGROUND: Endovascular treatment (EVT) is now considered the gold standard for select patient populations with anterior circulation stroke; however, data on the treatment of posterior circulation stroke are less clear. This study aims to determine the characteristics and treatment outcomes of patients with acute basilar artery occlusion (BAO) and to evaluate the effectiveness and safety of EVT for patients with acute BAO in a high-volume stroke center. METHODS: This study included 187 consecutive patients with acute BAO who underwent EVT from January 2012 to July 2018 in the Beijing Tiantan Hospital. The baseline characteristics, procedure parameters, and functional outcome were assessed. RESULTS: Among the 187 patients, 138 (73.8%) underwent mechanical thrombectomy with a stent retriever, 33 (17.6%) underwent direct intracranial angioplasty (balloon dilation and/or stent implantation) for underlying severe intracranial atherosclerotic disease, and 91 (48.7%) underwent combined mechanical thrombectomy and angioplasty. Successful recanalization [modified Thrombolysis in Cerebral Infarction (mTICI) grade 2b-3] was achieved in 158 patients (84.5%). Overall, the rates of functional independence [modified Rankin Scale (mRS) 0–2] and favorable outcome (mRS 0–3) at 90 days were 36.4 and 49.2%, respectively, and 90-day all-cause mortality was 20.3%. CONCLUSION: EVT was effective and safe for treating patients with acute BAO. BioMed Central 2019-12-06 /pmc/articles/PMC6898927/ /pubmed/31810447 http://dx.doi.org/10.1186/s12883-019-1551-8 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Sun, Xuan Tong, Xu Gao, Feng Lao, Huiting Miao, Zhongrong Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study |
title | Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study |
title_full | Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study |
title_fullStr | Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study |
title_full_unstemmed | Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study |
title_short | Endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study |
title_sort | endovascular treatment for acute basilar artery occlusion: a single center retrospective observational study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898927/ https://www.ncbi.nlm.nih.gov/pubmed/31810447 http://dx.doi.org/10.1186/s12883-019-1551-8 |
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