Cargando…
Cornel Iridoid Glycoside Protects Against White Matter Lesions Induced by Cerebral Ischemia in Rats via Activation of the Brain-Derived Neurotrophic Factor/Neuregulin-1 Pathway
BACKGROUND: Ischemic stroke often induces profound white matter lesions, resulting in poor neurological outcomes and impaired post-stroke recovery. The present study aimed to investigate the effects of cornel iridoid glycoside (CIG), a major active component extracted from Cornus officinalis, on the...
Autores principales: | Wang, Mingyang, Hua, Xuesi, Niu, Hongmei, Sun, Zhengyu, Zhang, Li, Li, Yali, Zhang, Lan, Li, Lin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898993/ https://www.ncbi.nlm.nih.gov/pubmed/31819458 http://dx.doi.org/10.2147/NDT.S228417 |
Ejemplares similares
-
Cornel iridoid glycoside ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by attenuating amyloid-beta, tau hyperphosphorylation and neurotrophic dysfunction
por: Yang, Cuicui, et al.
Publicado: (2020) -
Cornel Iridoid Glycoside Attenuates Tau Hyperphosphorylation by Inhibition of PP2A Demethylation
por: Yang, Cui-cui, et al.
Publicado: (2013) -
Cornel Iridoid Glycoside Improves Locomotor Impairment and Decreases Spinal Cord Damage in Rats
por: Tang, Wen-jing, et al.
Publicado: (2016) -
The Reduction of Tau Hyperphosphorylation by Cornel Iridoid Glycosides Is Mediated by Their Influence on Calpain Activity
por: Guo, Kaiwen, et al.
Publicado: (2022) -
Cornel Iridoid Glycoside Inhibits Tau Hyperphosphorylation via Regulating Cross-Talk Between GSK-3β and PP2A Signaling
por: Yang, Cuicui, et al.
Publicado: (2018)