Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam

Neonatal hydrocephalus affects about one child per 1000 births and is a major congenital brain abnormality. We previously discovered a gene mutation within the coiled-coil domain-containing 39 (Ccdc39) gene, which causes the progressive hydrocephalus (prh) phenotype in mice due to lack of ependymal-...

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Detalles Bibliográficos
Autores principales: Emmert, A. Scott, Iwasawa, Eri, Shula, Crystal, Schultz, Preston, Lindquist, Diana, Dunn, R. Scott, Fugate, Elizabeth M., Hu, Yueh-Chiang, Mangano, Francesco T., Goto, June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898999/
https://www.ncbi.nlm.nih.gov/pubmed/31771992
http://dx.doi.org/10.1242/dmm.040972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898999/
https://www.ncbi.nlm.nih.gov/pubmed/31771992
http://dx.doi.org/10.1242/dmm.040972

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