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Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease

Parkinson's disease (PD) is a basal ganglia movement disorder characterized by progressive degeneration of the nigrostriatal dopaminergic system. Immunohistochemical methods have been widely used for characterization of dopaminergic neuronal injury in animal models of PD, including the MPTP (1-...

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Detalles Bibliográficos
Autores principales: Roostalu, Urmas, Salinas, Casper B. G., Thorbek, Ditte D., Skytte, Jacob L., Fabricius, Katrine, Barkholt, Pernille, John, Linu M., Jurtz, Vanessa Isabell, Knudsen, Lotte Bjerre, Jelsing, Jacob, Vrang, Niels, Hansen, Henrik H., Hecksher-Sørensen, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899010/
https://www.ncbi.nlm.nih.gov/pubmed/31704726
http://dx.doi.org/10.1242/dmm.042200