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Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease
Parkinson's disease (PD) is a basal ganglia movement disorder characterized by progressive degeneration of the nigrostriatal dopaminergic system. Immunohistochemical methods have been widely used for characterization of dopaminergic neuronal injury in animal models of PD, including the MPTP (1-...
Autores principales: | Roostalu, Urmas, Salinas, Casper B. G., Thorbek, Ditte D., Skytte, Jacob L., Fabricius, Katrine, Barkholt, Pernille, John, Linu M., Jurtz, Vanessa Isabell, Knudsen, Lotte Bjerre, Jelsing, Jacob, Vrang, Niels, Hansen, Henrik H., Hecksher-Sørensen, Jacob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899010/ https://www.ncbi.nlm.nih.gov/pubmed/31704726 http://dx.doi.org/10.1242/dmm.042200 |
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