Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients

Hypertrophic cardiomyopathy (HCM) is a hereditary disease characterized by cardiac hypertrophy with diastolic dysfunction. Gene mutations causing HCM have been found in about half of HCM patients, while the genetic etiology and pathogenesis remain unknown for many cases of HCM. To identify novel mec...

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Detalles Bibliográficos
Autores principales: Higashikuse, Yuta, Mittal, Nishant, Arimura, Takuro, Yoon, Sung Han, Oda, Mayumi, Enomoto, Hirokazu, Kaneda, Ruri, Hattori, Fumiyuki, Suzuki, Takeshi, Kawakami, Atsushi, Gasch, Alexander, Furukawa, Tetsushi, Labeit, Siegfried, Fukuda, Keiichi, Kimura, Akinori, Makino, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899042/
https://www.ncbi.nlm.nih.gov/pubmed/31628103
http://dx.doi.org/10.1242/dmm.041103

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