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Tazarotene-Induced Gene 1 (TIG1) Interacts with Serine Protease Inhibitor Kazal-Type 2 (SPINK2) to Inhibit Cellular Invasion of Testicular Carcinoma Cells

Tazarotene-induced gene 1 (TIG1) encodes a protein that is a retinoid-regulated tumor suppressor. TIG1 is expressed in most normal tissues, and downregulation of TIG1 expression in multiple cancers is caused by promoter hypermethylation. Kazal-type serine protease inhibitor-2 (SPINK2) is a serine pr...

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Detalles Bibliográficos
Autores principales: Shyu, Rong-Yaun, Wang, Chun-Hua, Wu, Chang-Chieh, Wang, Lu-Kai, Chen, Mao-Liang, Kuo, Chan-Yen, Lee, Ming-Cheng, Lin, Yi-Ying, Tsai, Fu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899300/
https://www.ncbi.nlm.nih.gov/pubmed/31886233
http://dx.doi.org/10.1155/2019/6171065