Inhibition of PRMT5 Attenuates Oxidative Stress-Induced Pyroptosis via Activation of the Nrf2/HO-1 Signal Pathway in a Mouse Model of Renal Ischemia-Reperfusion Injury

BACKGROUND: Extensive evidence has demonstrated that oxidative stress, pyroptosis, and proinflammatory programmed cell death are related to renal ischemia/reperfusion (I/R) injury. However, the underlying mechanism remains to be illustrated. Protein arginine methylation transferase 5 (PRMT5), which...

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Detalles Bibliográficos
Autores principales: Diao, Changhui, Chen, Zhiyuan, Qiu, Tao, Liu, Hao, Yang, Yuanyuan, Liu, Xiuheng, Wu, Junfeng, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899313/
https://www.ncbi.nlm.nih.gov/pubmed/31885778
http://dx.doi.org/10.1155/2019/2345658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899313/
https://www.ncbi.nlm.nih.gov/pubmed/31885778
http://dx.doi.org/10.1155/2019/2345658

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