Cargando…
Psychoactive substance abuse and dependence and its association with anxiety disorders: a population-based study of young adults in Brazil
OBJECTIVE: To evaluate the association between abuse of and dependence on different psychoactive substances and the presence of anxiety disorders in a sample of young adults from a city in southern Brazil. METHODS: Between 2007 and 2009, we carried out a cross-sectional, population-based study of in...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Psiquiatria
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899384/ https://www.ncbi.nlm.nih.gov/pubmed/29451585 http://dx.doi.org/10.1590/1516-4446-2017-2258 |
_version_ | 1783477118247632896 |
---|---|
author | de Matos, Mariana B. de Mola, Christian L. Trettim, Jéssica P. Jansen, Karen da Silva, Ricardo A. de Mattos Souza, Luciano D. da Costa Ores, Liliane Molina, Mariane L. Coelho, Fernanda T. Pinheiro, Ricardo T. Quevedo, Luciana de A. |
author_facet | de Matos, Mariana B. de Mola, Christian L. Trettim, Jéssica P. Jansen, Karen da Silva, Ricardo A. de Mattos Souza, Luciano D. da Costa Ores, Liliane Molina, Mariane L. Coelho, Fernanda T. Pinheiro, Ricardo T. Quevedo, Luciana de A. |
author_sort | de Matos, Mariana B. |
collection | PubMed |
description | OBJECTIVE: To evaluate the association between abuse of and dependence on different psychoactive substances and the presence of anxiety disorders in a sample of young adults from a city in southern Brazil. METHODS: Between 2007 and 2009, we carried out a cross-sectional, population-based study of individuals aged 18-24 years who lived in Pelotas, a city in southern Brazil. We evaluated anxiety disorders using the Mini International Neuropsychiatric Interview 5.0 (MINI), and use of psychoactive substances with the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST 2.0/0MS). We used Fisher’s exact test for univariate analysis, and Poisson regression models with robust variance for multivariable analysis. RESULTS: The sample consisted of 1,560 young adults. The overall prevalence of abuse/dependence was 26.9% for alcohol, 24.9% for tobacco, and 7.3% for illicit substances. Individuals with agoraphobia had a 32% higher prevalence of tobacco abuse/dependence (prevalence ratio [PR] = 1.32 [95%CI 1.01-1.74]). Individuals with posttraumatic stress disorder (PTSD) or generalized anxiety disorder (GAD) had a 2.41-fold (95%CI 1.22-4.77) and 1.76-fold (95%CI 1.00-3.11) higher prevalence of illicit substance abuse/dependence, respectively. CONCLUSION: In this population-based sample, we found associations between GAD, PTSD, and increased prevalence of illicit substance abuse/dependence. In addition, individuals with agoraphobia seem to have increased tobacco abuse/dependence. |
format | Online Article Text |
id | pubmed-6899384 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Associação Brasileira de Psiquiatria |
record_format | MEDLINE/PubMed |
spelling | pubmed-68993842019-12-30 Psychoactive substance abuse and dependence and its association with anxiety disorders: a population-based study of young adults in Brazil de Matos, Mariana B. de Mola, Christian L. Trettim, Jéssica P. Jansen, Karen da Silva, Ricardo A. de Mattos Souza, Luciano D. da Costa Ores, Liliane Molina, Mariane L. Coelho, Fernanda T. Pinheiro, Ricardo T. Quevedo, Luciana de A. Braz J Psychiatry Original Article OBJECTIVE: To evaluate the association between abuse of and dependence on different psychoactive substances and the presence of anxiety disorders in a sample of young adults from a city in southern Brazil. METHODS: Between 2007 and 2009, we carried out a cross-sectional, population-based study of individuals aged 18-24 years who lived in Pelotas, a city in southern Brazil. We evaluated anxiety disorders using the Mini International Neuropsychiatric Interview 5.0 (MINI), and use of psychoactive substances with the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST 2.0/0MS). We used Fisher’s exact test for univariate analysis, and Poisson regression models with robust variance for multivariable analysis. RESULTS: The sample consisted of 1,560 young adults. The overall prevalence of abuse/dependence was 26.9% for alcohol, 24.9% for tobacco, and 7.3% for illicit substances. Individuals with agoraphobia had a 32% higher prevalence of tobacco abuse/dependence (prevalence ratio [PR] = 1.32 [95%CI 1.01-1.74]). Individuals with posttraumatic stress disorder (PTSD) or generalized anxiety disorder (GAD) had a 2.41-fold (95%CI 1.22-4.77) and 1.76-fold (95%CI 1.00-3.11) higher prevalence of illicit substance abuse/dependence, respectively. CONCLUSION: In this population-based sample, we found associations between GAD, PTSD, and increased prevalence of illicit substance abuse/dependence. In addition, individuals with agoraphobia seem to have increased tobacco abuse/dependence. Associação Brasileira de Psiquiatria 2018-02-15 /pmc/articles/PMC6899384/ /pubmed/29451585 http://dx.doi.org/10.1590/1516-4446-2017-2258 Text en http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article de Matos, Mariana B. de Mola, Christian L. Trettim, Jéssica P. Jansen, Karen da Silva, Ricardo A. de Mattos Souza, Luciano D. da Costa Ores, Liliane Molina, Mariane L. Coelho, Fernanda T. Pinheiro, Ricardo T. Quevedo, Luciana de A. Psychoactive substance abuse and dependence and its association with anxiety disorders: a population-based study of young adults in Brazil |
title | Psychoactive substance abuse and dependence and its association with anxiety disorders: a population-based study of young adults in Brazil |
title_full | Psychoactive substance abuse and dependence and its association with anxiety disorders: a population-based study of young adults in Brazil |
title_fullStr | Psychoactive substance abuse and dependence and its association with anxiety disorders: a population-based study of young adults in Brazil |
title_full_unstemmed | Psychoactive substance abuse and dependence and its association with anxiety disorders: a population-based study of young adults in Brazil |
title_short | Psychoactive substance abuse and dependence and its association with anxiety disorders: a population-based study of young adults in Brazil |
title_sort | psychoactive substance abuse and dependence and its association with anxiety disorders: a population-based study of young adults in brazil |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899384/ https://www.ncbi.nlm.nih.gov/pubmed/29451585 http://dx.doi.org/10.1590/1516-4446-2017-2258 |
work_keys_str_mv | AT dematosmarianab psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil AT demolachristianl psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil AT trettimjessicap psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil AT jansenkaren psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil AT dasilvaricardoa psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil AT demattossouzalucianod psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil AT dacostaoresliliane psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil AT molinamarianel psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil AT coelhofernandat psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil AT pinheiroricardot psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil AT quevedolucianadea psychoactivesubstanceabuseanddependenceanditsassociationwithanxietydisordersapopulationbasedstudyofyoungadultsinbrazil |