Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits

How neural circuits develop in the human brain has remained almost impossible to study at the neuronal level. Here, we investigate human cortical neuron development, plasticity, and function using a mouse/human chimera model in which xenotransplanted human cortical pyramidal neurons integrate as sin...

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Detalles Bibliográficos
Autores principales: Linaro, Daniele, Vermaercke, Ben, Iwata, Ryohei, Ramaswamy, Arjun, Libé-Philippot, Baptiste, Boubakar, Leila, Davis, Brittany A., Wierda, Keimpe, Davie, Kristofer, Poovathingal, Suresh, Penttila, Pier-Andrée, Bilheu, Angéline, De Bruyne, Lore, Gall, David, Conzelmann, Karl-Klaus, Bonin, Vincent, Vanderhaeghen, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899440/
https://www.ncbi.nlm.nih.gov/pubmed/31761708
http://dx.doi.org/10.1016/j.neuron.2019.10.002

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