TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions

MAIT cells are an unconventional T cell population that can be activated through both TCR-dependent and TCR-independent mechanisms. Here, we examined the impact of combinations of TCR-dependent and TCR-independent signals in human CD8(+) MAIT cells. TCR-independent activation of these MAIT cells fro...

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Detalles Bibliográficos
Autores principales: Leng, Tianqi, Akther, Hossain Delowar, Hackstein, Carl-Philipp, Powell, Kate, King, Thomas, Friedrich, Matthias, Christoforidou, Zoe, McCuaig, Sarah, Neyazi, Mastura, Arancibia-Cárcamo, Carolina V., Hagel, Joachim, Powrie, Fiona, Peres, Raphael Sanches, Millar, Val, Ebner, Daniel, Lamichhane, Rajesh, Ussher, James, Hinks, Timothy S.C., Marchi, Emanuele, Willberg, Chris, Klenerman, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899450/
https://www.ncbi.nlm.nih.gov/pubmed/31533032
http://dx.doi.org/10.1016/j.celrep.2019.08.050

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