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Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion

Lymph nodes (LNs) act as filters, constantly sampling peripheral cues. This is facilitated by the conduit network, a tubular structure of aligned extracellular matrix (ECM) fibrils ensheathed by fibroblastic reticular cells (FRCs). LNs undergo rapid 3- to 5-fold expansion during adaptive immune resp...

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Detalles Bibliográficos
Autores principales: Martinez, Victor G., Pankova, Valeriya, Krasny, Lukas, Singh, Tanya, Makris, Spyridon, White, Ian J., Benjamin, Agnesska C., Dertschnig, Simone, Horsnell, Harry L., Kriston-Vizi, Janos, Burden, Jemima J., Huang, Paul H., Tape, Christopher J., Acton, Sophie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899512/
https://www.ncbi.nlm.nih.gov/pubmed/31775047
http://dx.doi.org/10.1016/j.celrep.2019.10.103