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Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion
Lymph nodes (LNs) act as filters, constantly sampling peripheral cues. This is facilitated by the conduit network, a tubular structure of aligned extracellular matrix (ECM) fibrils ensheathed by fibroblastic reticular cells (FRCs). LNs undergo rapid 3- to 5-fold expansion during adaptive immune resp...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899512/ https://www.ncbi.nlm.nih.gov/pubmed/31775047 http://dx.doi.org/10.1016/j.celrep.2019.10.103 |