Cargando…
Fsp1-Mediated Lineage Tracing Fails to Detect the Majority of Disseminating Cells Undergoing EMT
Epithelial-to-mesenchymal transition (EMT) has long been thought to be crucial for metastasis. Recently a study challenged this idea by demonstrating that metastases were seeded by tumor cells that were not marked by an EMT lineage-tracing reporter on the basis of the expression of the mesenchymal m...
Autores principales: | Bornes, Laura, van Scheppingen, Roan Hugo, Beerling, Evelyne, Schelfhorst, Tim, Ellenbroek, Saskia Inge Johanna, Seinstra, Danielle, van Rheenen, Jacco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899519/ https://www.ncbi.nlm.nih.gov/pubmed/31775027 http://dx.doi.org/10.1016/j.celrep.2019.10.107 |
Ejemplares similares
-
Brief Report: Intravital Imaging of Cancer Stem Cell Plasticity in Mammary Tumors
por: Zomer, Anoek, et al.
Publicado: (2013) -
Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity
por: Beerling, Evelyne, et al.
Publicado: (2016) -
Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer
por: Fumagalli, Arianna, et al.
Publicado: (2020) -
Intravital FRET Imaging of Tumor Cell Viability and Mitosis during Chemotherapy
por: Janssen, Aniek, et al.
Publicado: (2013) -
Intravital characterization of tumor cell migration in pancreatic cancer
por: Beerling, Evelyne, et al.
Publicado: (2016)