Structure‐Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases

Human histone demethylases are known to play an important role in the development of several tumor types. Consequently, they have emerged as important medical targets for the treatment of human cancer. Herein, structural studies on tetrazolylhydrazide inhibitors as a new scaffold for a certain class...

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Detalles Bibliográficos
Autores principales: Małecki, Piotr H., Rüger, Nicole, Roatsch, Martin, Krylova, Oxana, Link, Andreas, Jung, Manfred, Heinemann, Udo, Weiss, Manfred S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899576/
https://www.ncbi.nlm.nih.gov/pubmed/31475772
http://dx.doi.org/10.1002/cmdc.201900441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899576/
https://www.ncbi.nlm.nih.gov/pubmed/31475772
http://dx.doi.org/10.1002/cmdc.201900441

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