Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

A substantial challenge worldwide is emergent drug resistance in malaria parasites against approved drugs, such as chloroquine (CQ). To address these unsolved CQ resistance issues, only rare examples of artemisinin (ART)‐based hybrids have been reported. Moreover, protein targets of such hybrids hav...

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Detalles Bibliográficos
Autores principales: Çapcı, Aysun, Lorion, Mélanie M., Wang, Hui, Simon, Nina, Leidenberger, Maria, Borges Silva, Mariana C., Moreira, Diogo R. M., Zhu, Yongping, Meng, Yuqing, Chen, Jia Yun, Lee, Yew Mun, Friedrich, Oliver, Kappes, Barbara, Wang, Jigang, Ackermann, Lutz, Tsogoeva, Svetlana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899722/
https://www.ncbi.nlm.nih.gov/pubmed/31290221
http://dx.doi.org/10.1002/anie.201907224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899722/
https://www.ncbi.nlm.nih.gov/pubmed/31290221
http://dx.doi.org/10.1002/anie.201907224

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