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Synthesis of Benzo[b]azocin‐2‐ones by Aryl Amination and Ring‐Expansion of α‐(Iodophenyl)‐β‐oxoesters

Transformation of β‐oxoesters with PhI(OCOCF(3))(2) leads to α‐(ortho‐iodophenyl)‐β‐oxoesters. These materials are the starting point for the synthesis of 6‐carboxybenzo[b]azocin‐2‐ones by a sequence of aryl amination and ring transformation. This reaction sequence starts with copper‐catalyzed forma...

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Detalles Bibliográficos
Autores principales:	Dierks, Anna, Tönjes, Jan, Schmidtmann, Marc, Christoffers, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899745/ https://www.ncbi.nlm.nih.gov/pubmed/31433088 http://dx.doi.org/10.1002/chem.201903139

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