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Genetic background modifies CNS‐mediated sensorimotor decline in the AD‐BXD mouse model of genetic diversity in Alzheimer's disease

Many patients with Alzheimer's dementia (AD) also exhibit noncognitive symptoms such as sensorimotor deficits, which can precede the hallmark cognitive deficits and significantly impact daily activities and an individual's ability to live independently. However, the mechanisms underlying s...

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Detalles Bibliográficos
Autores principales: O'Connell, Kristen M. S., Ouellette, Andrew R., Neuner, Sarah M., Dunn, Amy R., Kaczorowski, Catherine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899779/
https://www.ncbi.nlm.nih.gov/pubmed/31381246
http://dx.doi.org/10.1111/gbb.12603