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A Phenotypic Switch of Differentiated Glial Cells to Dedifferentiated Cells Is Regulated by Folate Receptor α
In a previous study, we showed that folate receptor‐α (FRα) translocates to the nucleus where it acts as a transcription factor and upregulates Hes1, Oct4, Sox2, and Klf4 genes responsible for pluripotency. Here, we show that acetylation and phosphorylation of FRα favor its nuclear translocation in...
Autores principales: | Monick, Sarah, Mohanty, Vineet, Khan, Mariam, Yerneni, Gowtham, Kumar, Raj, Cantu, Jorge, Ichi, Shunsuke, Xi, Guifa, Singh, Bal Ram, Tomita, Tadanori, Mayanil, Chandra Shekhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899875/ https://www.ncbi.nlm.nih.gov/pubmed/31381815 http://dx.doi.org/10.1002/stem.3067 |
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