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MRI‐based transfer function determination through the transfer matrix by jointly fitting the incident and scattered [Formula: see text] field

PURPOSE: A purely experimental method for MRI‐based transfer function (TF) determination is presented. A TF characterizes the potential for radiofrequency heating of a linear implant by relating the incident tangential electric field to a scattered electric field at its tip. We utilize the previousl...

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Autores principales: Tokaya, Janot P., Raaijmakers, Alexander J.E., Luijten, Peter R., Sbrizzi, Alessandro, van den Berg, Cornelis A.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899904/
https://www.ncbi.nlm.nih.gov/pubmed/31631400
http://dx.doi.org/10.1002/mrm.27974
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author Tokaya, Janot P.
Raaijmakers, Alexander J.E.
Luijten, Peter R.
Sbrizzi, Alessandro
van den Berg, Cornelis A.T.
author_facet Tokaya, Janot P.
Raaijmakers, Alexander J.E.
Luijten, Peter R.
Sbrizzi, Alessandro
van den Berg, Cornelis A.T.
author_sort Tokaya, Janot P.
collection PubMed
description PURPOSE: A purely experimental method for MRI‐based transfer function (TF) determination is presented. A TF characterizes the potential for radiofrequency heating of a linear implant by relating the incident tangential electric field to a scattered electric field at its tip. We utilize the previously introduced transfer matrix (TM) to determine transfer functions solely from the MR measurable quantities, that is, the [Formula: see text] and transceive phase distributions. This technique can extend the current practice of phantom‐based TF assessment with dedicated experimental setup toward MR‐based methods that have the potential to assess the TF in more realistic situations. THEORY AND METHODS: An analytical description of the [Formula: see text] magnitude and transceive phase distribution around a wire‐like implant was derived based on the TM. In this model, the background field is described using a superposition of spherical and cylindrical harmonics while the transfer matrix is parameterized using a previously introduced attenuated wave model. This analytical description can be used to estimate the transfer matrix and transfer function based on the measured [Formula: see text] distribution. RESULTS: The TF was successfully determined for 2 mock‐up implants: a 20‐cm bare copper wire and a 20‐cm insulated copper wire with 10 mm of insulation stripped at both endings in respectively 4 and 3 different trajectories. The measured TFs show a strong correlation with a reference determined from simulations and between the separate experiments with correlation coefficients above 0.96 between all TFs. Compared to the simulated TF, the maximum deviation in the estimated tip field is 9.4% and 12.2% for the bare and insulated wire, respectively. CONCLUSIONS: A method has been developed to measure the TF of medical implants using MRI experiments. Jointly fitting the incident and scattered [Formula: see text] distributions with an analytical description based on the transfer matrix enables accurate determination of the TF of 2 test implants. The presented method no longer needs input from simulated data and can therefore, in principle, be used to measure TF's in test animals or corpses.
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spelling pubmed-68999042019-12-19 MRI‐based transfer function determination through the transfer matrix by jointly fitting the incident and scattered [Formula: see text] field Tokaya, Janot P. Raaijmakers, Alexander J.E. Luijten, Peter R. Sbrizzi, Alessandro van den Berg, Cornelis A.T. Magn Reson Med Full Papers—Biophysics and Basic Biomedical Research PURPOSE: A purely experimental method for MRI‐based transfer function (TF) determination is presented. A TF characterizes the potential for radiofrequency heating of a linear implant by relating the incident tangential electric field to a scattered electric field at its tip. We utilize the previously introduced transfer matrix (TM) to determine transfer functions solely from the MR measurable quantities, that is, the [Formula: see text] and transceive phase distributions. This technique can extend the current practice of phantom‐based TF assessment with dedicated experimental setup toward MR‐based methods that have the potential to assess the TF in more realistic situations. THEORY AND METHODS: An analytical description of the [Formula: see text] magnitude and transceive phase distribution around a wire‐like implant was derived based on the TM. In this model, the background field is described using a superposition of spherical and cylindrical harmonics while the transfer matrix is parameterized using a previously introduced attenuated wave model. This analytical description can be used to estimate the transfer matrix and transfer function based on the measured [Formula: see text] distribution. RESULTS: The TF was successfully determined for 2 mock‐up implants: a 20‐cm bare copper wire and a 20‐cm insulated copper wire with 10 mm of insulation stripped at both endings in respectively 4 and 3 different trajectories. The measured TFs show a strong correlation with a reference determined from simulations and between the separate experiments with correlation coefficients above 0.96 between all TFs. Compared to the simulated TF, the maximum deviation in the estimated tip field is 9.4% and 12.2% for the bare and insulated wire, respectively. CONCLUSIONS: A method has been developed to measure the TF of medical implants using MRI experiments. Jointly fitting the incident and scattered [Formula: see text] distributions with an analytical description based on the transfer matrix enables accurate determination of the TF of 2 test implants. The presented method no longer needs input from simulated data and can therefore, in principle, be used to measure TF's in test animals or corpses. John Wiley and Sons Inc. 2019-10-21 2020-03 /pmc/articles/PMC6899904/ /pubmed/31631400 http://dx.doi.org/10.1002/mrm.27974 Text en © 2019 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Full Papers—Biophysics and Basic Biomedical Research
Tokaya, Janot P.
Raaijmakers, Alexander J.E.
Luijten, Peter R.
Sbrizzi, Alessandro
van den Berg, Cornelis A.T.
MRI‐based transfer function determination through the transfer matrix by jointly fitting the incident and scattered [Formula: see text] field
title MRI‐based transfer function determination through the transfer matrix by jointly fitting the incident and scattered [Formula: see text] field
title_full MRI‐based transfer function determination through the transfer matrix by jointly fitting the incident and scattered [Formula: see text] field
title_fullStr MRI‐based transfer function determination through the transfer matrix by jointly fitting the incident and scattered [Formula: see text] field
title_full_unstemmed MRI‐based transfer function determination through the transfer matrix by jointly fitting the incident and scattered [Formula: see text] field
title_short MRI‐based transfer function determination through the transfer matrix by jointly fitting the incident and scattered [Formula: see text] field
title_sort mri‐based transfer function determination through the transfer matrix by jointly fitting the incident and scattered [formula: see text] field
topic Full Papers—Biophysics and Basic Biomedical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899904/
https://www.ncbi.nlm.nih.gov/pubmed/31631400
http://dx.doi.org/10.1002/mrm.27974
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