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A Chemical Biology Approach to Understanding Molecular Recognition of Lipid II by Nisin(1–12): Synthesis and NMR Ensemble Analysis of Nisin(1–12) and Analogues

Natural products that target lipid II, such as the lantibiotic nisin, are strategically important in the development of new antibacterial agents to combat the rise of antimicrobial resistance. Understanding the structural factors that govern the highly selective molecular recognition of lipid II by...

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Detalles Bibliográficos
Autores principales: Dickman, Rachael, Danelius, Emma, Mitchell, Serena A., Hansen, D. Flemming, Erdélyi, Máté, Tabor, Alethea B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899958/
https://www.ncbi.nlm.nih.gov/pubmed/31599485
http://dx.doi.org/10.1002/chem.201902814