Synthesis of Indomorphan Pseudo‐Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3

Bioactive compound design based on natural product (NP) structure may be limited because of partial coverage of NP‐like chemical space and biological target space. These limitations can be overcome by combining NP‐centered strategies with fragment‐based compound design through combination of NP‐deri...

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Detalles Bibliográficos
Autores principales: Ceballos, Javier, Schwalfenberg, Melanie, Karageorgis, George, Reckzeh, Elena S., Sievers, Sonja, Ostermann, Claude, Pahl, Axel, Sellstedt, Magnus, Nowacki, Jessica, Carnero Corrales, Marjorie A., Wilke, Julian, Laraia, Luca, Tschapalda, Kirsten, Metz, Malte, Sehr, Dominik A., Brand, Silke, Winklhofer, Konstanze, Janning, Petra, Ziegler, Slava, Waldmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900016/
https://www.ncbi.nlm.nih.gov/pubmed/31469221
http://dx.doi.org/10.1002/anie.201909518

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