Cargando…
CAGI5: Objective performance assessments of predictions based on the Evolutionary Action equation
Many computational approaches estimate the effect of coding variants, but their predictions often disagree with each other. These contradictions confound users and raise questions regarding reliability. Performance assessments can indicate the expected accuracy for each method and highlight advantag...
Autores principales: | Katsonis, Panagiotis, Lichtarge, Olivier |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900054/ https://www.ncbi.nlm.nih.gov/pubmed/31317604 http://dx.doi.org/10.1002/humu.23873 |
Ejemplares similares
-
A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness
por: Katsonis, Panagiotis, et al.
Publicado: (2014) -
CAGI6 ID-Challenge: Assessment of phenotype and variant predictions in 415 children with Neurodevelopmental Disorders (NDDs)
por: Aspromonte, Maria Cristina, et al.
Publicado: (2023) -
EPIMUTESTR: a nearest neighbor machine learning approach to predict cancer driver genes from the evolutionary action of coding variants
por: Parvandeh, Saeid, et al.
Publicado: (2022) -
Inauguration of the CAGI Welcome Centre of International Geneva
por: CAVAZZA, Marina
Publicado: (2022) -
Genome interpretation using in silico predictors of variant impact
por: Katsonis, Panagiotis, et al.
Publicado: (2022)