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Management of Tamm–Horsfall Protein for Reliable Urinary Analytics

PURPOSE: Urinary extracellular vesicles (uEVs) are a novel source of biomarkers. However, urinary Tamm–Horsfall Protein (THP; uromodulin) interferes with all vesicle isolation attempts, precipitates with normal urinary proteins, thus, representing an unwanted “contaminant” in urinary assays. Thus, t...

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Detalles Bibliográficos
Autores principales: Xu, Xiaomeng, Barreiro, Karina, Musante, Luca, Kretz, Oliver, Lin, Hanfei, Zou, Hequn, Huber, Tobias B., Holthofer, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900072/
https://www.ncbi.nlm.nih.gov/pubmed/31424164
http://dx.doi.org/10.1002/prca.201900018