Photochemical C−H Hydroxyalkylation of Quinolines and Isoquinolines

We report herein a visible light‐mediated C−H hydroxyalkylation of quinolines and isoquinolines that proceeds via a radical path. The process exploits the excited‐state reactivity of 4‐acyl‐1,4‐dihydropyridines, which can readily generate acyl radicals upon blue light absorption. By avoiding the nee...

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Detalles Bibliográficos
Autores principales: Bieszczad, Bartosz, Perego, Luca Alessandro, Melchiorre, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900123/
https://www.ncbi.nlm.nih.gov/pubmed/31529788
http://dx.doi.org/10.1002/anie.201910641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900123/
https://www.ncbi.nlm.nih.gov/pubmed/31529788
http://dx.doi.org/10.1002/anie.201910641

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