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Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation

INTRODUCTION: Physical inactivity significantly contributes to loss of muscle mass and performance in bed‐bound patients. Loss of skeletal muscle mitochondrial content has been well‐established in muscle unloading models, but the underlying molecular mechanism remains unclear. We hypothesized that a...

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Detalles Bibliográficos
Autores principales:	Leermakers, Pieter A., Kneppers, Anita E.M., Schols, Annemie M.W.J., Kelders, Marco C.J.M., de Theije, Chiel C., Verdijk, Lex B., van Loon, Luc J.C., Langen, Ramon C.J., Gosker, Harry R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Basic Science Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900132/ https://www.ncbi.nlm.nih.gov/pubmed/31495926 http://dx.doi.org/10.1002/mus.26702

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