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Reversible Covalent End‐Capping of Collagen Model Peptides

The combination of supramolecular aggregation of collagen model peptides with reversible covalent end‐capping of the formed triple helix in a single experimental set‐up yielded minicollagens, which were characterized by a single melting temperature. In spite of the numerous possible reaction interme...

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Detalles Bibliográficos
Autores principales: Priem, Christoph, Geyer, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900188/
https://www.ncbi.nlm.nih.gov/pubmed/31557356
http://dx.doi.org/10.1002/chem.201903460
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author Priem, Christoph
Geyer, Armin
author_facet Priem, Christoph
Geyer, Armin
author_sort Priem, Christoph
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description The combination of supramolecular aggregation of collagen model peptides with reversible covalent end‐capping of the formed triple helix in a single experimental set‐up yielded minicollagens, which were characterized by a single melting temperature. In spite of the numerous possible reaction intermediates, a specific synthetic collagen with a leading, middle and trailing strand is formed in a highly cooperative self‐assembly process.
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spelling pubmed-69001882019-12-20 Reversible Covalent End‐Capping of Collagen Model Peptides Priem, Christoph Geyer, Armin Chemistry Communications The combination of supramolecular aggregation of collagen model peptides with reversible covalent end‐capping of the formed triple helix in a single experimental set‐up yielded minicollagens, which were characterized by a single melting temperature. In spite of the numerous possible reaction intermediates, a specific synthetic collagen with a leading, middle and trailing strand is formed in a highly cooperative self‐assembly process. John Wiley and Sons Inc. 2019-10-17 2019-11-13 /pmc/articles/PMC6900188/ /pubmed/31557356 http://dx.doi.org/10.1002/chem.201903460 Text en © 2019 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Communications
Priem, Christoph
Geyer, Armin
Reversible Covalent End‐Capping of Collagen Model Peptides
title Reversible Covalent End‐Capping of Collagen Model Peptides
title_full Reversible Covalent End‐Capping of Collagen Model Peptides
title_fullStr Reversible Covalent End‐Capping of Collagen Model Peptides
title_full_unstemmed Reversible Covalent End‐Capping of Collagen Model Peptides
title_short Reversible Covalent End‐Capping of Collagen Model Peptides
title_sort reversible covalent end‐capping of collagen model peptides
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900188/
https://www.ncbi.nlm.nih.gov/pubmed/31557356
http://dx.doi.org/10.1002/chem.201903460
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