Visible Light Induced Metal-Free Carbene N-Carbazolation

[Image: see text] Metal-free N–H functionalization reactions represent an important strategy for sustainable C–N coupling reactions. In this report, we describe the visible light photolysis of aryl diazoacetates in the presence of some N-heterocycles that enables mild, metal-free N–H functionalizati...

Descripción completa

Detalles Bibliográficos
Autores principales: Empel, Claire, Patureau, Frederic W., Koenigs, Rene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900254/
https://www.ncbi.nlm.nih.gov/pubmed/31373201
http://dx.doi.org/10.1021/acs.joc.9b01753
_version_ 1783477315229974528
author Empel, Claire
Patureau, Frederic W.
Koenigs, Rene M.
author_facet Empel, Claire
Patureau, Frederic W.
Koenigs, Rene M.
author_sort Empel, Claire
collection PubMed
description [Image: see text] Metal-free N–H functionalization reactions represent an important strategy for sustainable C–N coupling reactions. In this report, we describe the visible light photolysis of aryl diazoacetates in the presence of some N-heterocycles that enables mild, metal-free N–H functionalization reactions of carbazole and azepine heterocycles (15 examples, up to 83% yield).
format Online
Article
Text
id pubmed-6900254
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-69002542019-12-10 Visible Light Induced Metal-Free Carbene N-Carbazolation Empel, Claire Patureau, Frederic W. Koenigs, Rene M. J Org Chem [Image: see text] Metal-free N–H functionalization reactions represent an important strategy for sustainable C–N coupling reactions. In this report, we describe the visible light photolysis of aryl diazoacetates in the presence of some N-heterocycles that enables mild, metal-free N–H functionalization reactions of carbazole and azepine heterocycles (15 examples, up to 83% yield). American Chemical Society 2019-08-02 2019-09-06 /pmc/articles/PMC6900254/ /pubmed/31373201 http://dx.doi.org/10.1021/acs.joc.9b01753 Text en Copyright © 2019 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Empel, Claire
Patureau, Frederic W.
Koenigs, Rene M.
Visible Light Induced Metal-Free Carbene N-Carbazolation
title Visible Light Induced Metal-Free Carbene N-Carbazolation
title_full Visible Light Induced Metal-Free Carbene N-Carbazolation
title_fullStr Visible Light Induced Metal-Free Carbene N-Carbazolation
title_full_unstemmed Visible Light Induced Metal-Free Carbene N-Carbazolation
title_short Visible Light Induced Metal-Free Carbene N-Carbazolation
title_sort visible light induced metal-free carbene n-carbazolation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900254/
https://www.ncbi.nlm.nih.gov/pubmed/31373201
http://dx.doi.org/10.1021/acs.joc.9b01753
work_keys_str_mv AT empelclaire visiblelightinducedmetalfreecarbenencarbazolation
AT patureaufredericw visiblelightinducedmetalfreecarbenencarbazolation
AT koenigsrenem visiblelightinducedmetalfreecarbenencarbazolation

Ejemplares similares