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Effect of non-synonymous SNP on JAK1 protein structure and subsequent function

JAK1 gene plays a critical role in signalling. Malfunction of JAK1 is linked to numerous human diseases ranging from chronic inflammation to cancers and autoimmune diseases. Genetic variations in JAK1 exhibit deleterious effects on gene function leading to the deregulation of signalling pathways. A...

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Detalles Bibliográficos
Autores principales:	Liza, Rozario, Tanima, Sharker, Tahsin, Nairuz, Reaz, Morshed Md
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900321/ https://www.ncbi.nlm.nih.gov/pubmed/31831954 http://dx.doi.org/10.6026/97320630015723

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