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Linking Helicobacter pylori with gallbladder and biliary tract cancer in Moroccan population using clinical and pathological profiles

It is of interest to assess the clinical and pathological aspects of Gallbladder and biliary tract carcinomas confirmed by histological data. It is also of further interest to evaluate the link between Helicobacter pylori and biliary tract cancers. Eighty-nine (89) cases (mean age 60±12 years) of Ga...

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Autores principales: Cherif, Soumia, Rais, Hanane, Hakmaoui, Abdelmalk, Sellami, Souad, Elantri, Said, Amine, Abdessamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900325/
https://www.ncbi.nlm.nih.gov/pubmed/31831956
http://dx.doi.org/10.6026/97320630015735
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author Cherif, Soumia
Rais, Hanane
Hakmaoui, Abdelmalk
Sellami, Souad
Elantri, Said
Amine, Abdessamad
author_facet Cherif, Soumia
Rais, Hanane
Hakmaoui, Abdelmalk
Sellami, Souad
Elantri, Said
Amine, Abdessamad
author_sort Cherif, Soumia
collection PubMed
description It is of interest to assess the clinical and pathological aspects of Gallbladder and biliary tract carcinomas confirmed by histological data. It is also of further interest to evaluate the link between Helicobacter pylori and biliary tract cancers. Eighty-nine (89) cases (mean age 60±12 years) of Gallbladder and biliary tract cancer confirmed by histological data were enrolled for the study at the Department of Pathology in Mohammed VI University Hospital, in Morocco. The data such as age, sex, clinical and histo pathological features were collected. Bile duct specimens were investigated for H. pylori using Giemsa and immuno histo chemistry staining. Results show that bile duct stones were found in 53.9% of cases. It is known using histological data that adeno carcinoma is common accounting for 70 % of all bile duct tumors. Moreover, Helicobacter pylori was detected in 54% of cases linking with the presence of bile duct stones characterized by the histological subtype, the macroscopic classification and lymph node's presence (p<0.001). Thus, data collected suggest the potential association of Helicobacter pylori with gallbladder cancer possibly through the formation of bile duct stones.
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spelling pubmed-69003252019-12-12 Linking Helicobacter pylori with gallbladder and biliary tract cancer in Moroccan population using clinical and pathological profiles Cherif, Soumia Rais, Hanane Hakmaoui, Abdelmalk Sellami, Souad Elantri, Said Amine, Abdessamad Bioinformation Research Article It is of interest to assess the clinical and pathological aspects of Gallbladder and biliary tract carcinomas confirmed by histological data. It is also of further interest to evaluate the link between Helicobacter pylori and biliary tract cancers. Eighty-nine (89) cases (mean age 60±12 years) of Gallbladder and biliary tract cancer confirmed by histological data were enrolled for the study at the Department of Pathology in Mohammed VI University Hospital, in Morocco. The data such as age, sex, clinical and histo pathological features were collected. Bile duct specimens were investigated for H. pylori using Giemsa and immuno histo chemistry staining. Results show that bile duct stones were found in 53.9% of cases. It is known using histological data that adeno carcinoma is common accounting for 70 % of all bile duct tumors. Moreover, Helicobacter pylori was detected in 54% of cases linking with the presence of bile duct stones characterized by the histological subtype, the macroscopic classification and lymph node's presence (p<0.001). Thus, data collected suggest the potential association of Helicobacter pylori with gallbladder cancer possibly through the formation of bile duct stones. Biomedical Informatics 2019-10-31 /pmc/articles/PMC6900325/ /pubmed/31831956 http://dx.doi.org/10.6026/97320630015735 Text en © 2019 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Cherif, Soumia
Rais, Hanane
Hakmaoui, Abdelmalk
Sellami, Souad
Elantri, Said
Amine, Abdessamad
Linking Helicobacter pylori with gallbladder and biliary tract cancer in Moroccan population using clinical and pathological profiles
title Linking Helicobacter pylori with gallbladder and biliary tract cancer in Moroccan population using clinical and pathological profiles
title_full Linking Helicobacter pylori with gallbladder and biliary tract cancer in Moroccan population using clinical and pathological profiles
title_fullStr Linking Helicobacter pylori with gallbladder and biliary tract cancer in Moroccan population using clinical and pathological profiles
title_full_unstemmed Linking Helicobacter pylori with gallbladder and biliary tract cancer in Moroccan population using clinical and pathological profiles
title_short Linking Helicobacter pylori with gallbladder and biliary tract cancer in Moroccan population using clinical and pathological profiles
title_sort linking helicobacter pylori with gallbladder and biliary tract cancer in moroccan population using clinical and pathological profiles
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900325/
https://www.ncbi.nlm.nih.gov/pubmed/31831956
http://dx.doi.org/10.6026/97320630015735
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