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Identification of a novel somatic mutation of POU6F2 by whole‐genome sequencing in prolactinoma

BACKGROUND: Pituitary adenomas (PAs) are one of the most common intracranial tumors; approximately half of PAs are prolactin (PRL)‐secreting PAs (prolactinomas). The genetic alterations prevalent in prolactinomas are unknown. METHODS: Here, we present a patient with an extremely aggressive and giant...

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Detalles Bibliográficos
Autores principales: Miao, Yazhou, Li, Chuzhong, Guo, Jing, Wang, Hongyun, Gong, Lei, Xie, Weiyan, Zhang, Yazhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900357/
https://www.ncbi.nlm.nih.gov/pubmed/31692290
http://dx.doi.org/10.1002/mgg3.1022