Cargando…
Dcp2: an mRNA decapping enzyme that adopts many different shapes and forms
Eukaryotic mRNAs contain a 5’ cap structure that protects the transcript against rapid exonucleolytic degradation. The regulation of cellular mRNA levels therefore depends on a precise control of the mRNA decapping pathways. The major mRNA decapping enzyme in eukaryotic cells is Dcp2. It is regulate...
Autores principales: | Wurm, Jan Philip, Sprangers, Remco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900585/ https://www.ncbi.nlm.nih.gov/pubmed/31473440 http://dx.doi.org/10.1016/j.sbi.2019.07.009 |
Ejemplares similares
-
Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme
por: Fuchs, Anna-Lisa, et al.
Publicado: (2020) -
The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface
por: Wurm, Jan Philip, et al.
Publicado: (2016) -
Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2)
por: Gunawardana, Dilantha, et al.
Publicado: (2008) -
The human decapping scavenger enzyme DcpS modulates microRNA turnover
por: Meziane, Oussama, et al.
Publicado: (2015) -
Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS
por: Taverniti, Valerio, et al.
Publicado: (2015)