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Four-dimensional analyses show that replication compartments are clonal factories in which Epstein–Barr viral DNA amplification is coordinated
Herpesviruses must amplify their DNA to load viral particles and they do so in replication compartments. The development and functions of replication compartments during DNA amplification are poorly understood, though. Here we examine 2 functionally distinct replicons in the same cells to dissect DN...
Autores principales: | Nagaraju, Thejaswi, Sugden, Arthur U., Sugden, Bill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900597/ https://www.ncbi.nlm.nih.gov/pubmed/31744871 http://dx.doi.org/10.1073/pnas.1913992116 |
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